rehabilitation engineers

Abstract: Decoding simultaneous and proportional finger kinematics from high-density surface electromyography (HD sEMG) remains challenging. Although data-driven methods have shown promising performance for finger movement decoding, their limited physiological interpretability remains a relevant limitation. This study proposes and evaluates a spiking neural network (SNN) that incorporates spinal-inspired structures and mechanisms to predict multi-joint finger kinematics from HD sEMG signals. The spinal-inspired SNN includes a spike-encoding computational model with input-noise variability, a phenomenological representation of Henneman's size principle, and excitation/inhibition (E/I) balance. HD sEMG and kinematic data were collected from 23 healthy participants performing grasping tasks under different elbow and wrist postures. Performance was assessed using six prediction metrics and compared against six baseline machine learning and deep learning methods. The proposed method showed a large and significant ($p<0.05$, rank-biserial correlation $r_{rb}>0.7$) improvement over all baseline methods across all accuracy metrics. Performance improved significantly with increasing spike encoder firing rates up to approximately 128 Hz, and with more regular input spike trains compared with a Poisson-like encoder. In contrast, the E/I balance did not significantly affect the decoding performance of the algorithm. The firing rate and inter-spike interval statistics of the SNN differed significantly across motor tasks. These results demonstrate that incorporating neurophysiological principles into SNNs improves prediction performance while providing additional physiological interpretability for simultaneous and proportional finger-kinematics decoding. This approach represents a promising step toward physiology-informed neural networks, with potential applications in motor rehabilitation.

Abstract: Accurate human torque estimation is crucial for enabling task-agnostic control in robotic exoskeleton systems. However, estimation errors may cause mismatches between the robot assistance and the human intention, degrading controllability and task performance. In this paper, we address this issue by formally defining matched assistance as scenarios in which the robot positively contributes to human movement. Based on this definition, we develop a theoretical framework to design the robot's desired interaction torque that guarantees a lower bound on the matched assistance probability. Importantly, the proposed guarantee holds over the entire torque distribution, including unseen data beyond the training tasks. This provides our method with strong reliability and generalization, both of which are critical for effective exoskeleton control. The proposed strategy is implemented on the ABLE upper-limb exoskeleton and evaluated in a multi-task setup. Experimental results validate the theoretical guarantees and demonstrate that the proposed strategy achieves effective general performance across several tasks, guaranteeing movement smoothness while reducing human physical effort.

Abstract: Providing personalized exoskeleton assistance across varying walking speeds remains challenging. Existing online optimization methods are sample-inefficient, requiring extensive human-in-the-loop (HIL) evaluations to optimize the entire assistive torque profile. Sim-to-real reinforcement learning (RL) offers a promising alternative but cannot directly account for individual user preferences. We propose a framework integrating sim-to-real RL with online preference learning for personalized exoskeleton assistance. Specifically, assistance timing is learned in simulation by training RL policies with human musculoskeletal models across varying walking speeds. The learned policies are then distilled and deployed on a physical hip exoskeleton using onboard sensory observations. Gaussian-process-based preference learning further personalizes the assistance magnitude through pairwise user comparisons. By decoupling assistance timing learning in simulation from magnitude optimization in real-world experiments, our framework substantially reduces the online optimization space. Human-subject experiments demonstrate efficient identification of personalized assistive torque profiles across varying walking speeds with fewer real-world evaluations.

Abstract: Providing safe and effective mobility assistance plays a crucial role in restoring independence and enhancing the quality of life for individuals with motor impairments. In this context, robotic walking assistive devices have recently emerged as promising solutions to provide physically compliant interaction while ensuring user safety and support. This paper presents a novel control framework for an omnidirectional Walking Assistive Robot (I-WANDER) that integrates a Control Barrier Function (CBF) formulation into a Model Predictive Control (MPC) scheme to explicitly enforce collision-avoidance safety constraints while optimizing for energy efficiency and smooth human-robot collaboration. The method was experimentally evaluated with 12 healthy participants performing two different walking tasks using both the proposed CBF-based MPC controller (CB-MPC) and a variable admittance controller (AC). The first task involved structured navigation through a U-shaped corridor, whereas the second consisted of a single-obstacle avoidance task performed blindfolded to ensure the obstacle was unexpected. Comparative results show that the CB-MPC architecture significantly reduces energy consumption and mechanical work (p < 0.01) without compromising motion smoothness, while also decreasing the number of obstacle collisions. Overall, the findings highlight the potential of the proposed control architecture to enhance both safety and efficiency in robotic walking assistance.

Abstract: Biological torque control directly maps an estimated human joint moment to exoskeleton assistance, providing a task-agnostic strategy for supporting diverse locomotor activities. However, it remains unclear whether a fixed state-to-torque mapping provides effective assistance across biomechanically distinct tasks. We examined how assistance delay affected hip exoskeleton performance during level-ground (LG), ramp-ascent (RA), and ramp-descent (RD) walking. Eight participants completed a zero-torque baseline condition and five active assistance conditions with delays ranging from 40 to 320 ms. Across tasks and active delays, assistance reduced net metabolic rate by 5.24%, positive biological hip joint work by 5.86%, and total lower-limb positive joint work by 1.68% (all p < 0.05). Assistance delay affected both joint-work outcomes (both p < 0.001) but not net metabolic rate. Mechanical unloading generally decreased with increasing delay, whereas metabolic benefits remained comparatively stable. Relative to the zero-torque condition, net metabolic rate decreased by 9.75% during LG and 7.20% during RA but increased by 1.23% during RD. We did not detect task-dependent differences in the delay response. Our findings indicate that biological torque mappings should be evaluated based on the target outcome and mechanical role of the assisted joint, and that predominantly positive-power assistance may not generalize to negative-work-dominant locomotion without modification.

Abstract: This study evaluated personalized gait phase estimation for stroke survivors using functional inertial measurement unit (IMU) alignment and two-stage sequential adaptation of models pre-trained on healthy gait. The estimator used signals from a thigh-mounted IMU. Heel force-sensitive resistor measurements provided reference phase labels for offline adaptation and evaluation. Stage 1 established a distillation-regularized participant-specific model, and Stage 2 performed conditional refinement using low-rank adaptation. Long Short-Term Memory (LSTM), Temporal Convolutional Network (TCN), and Transformer models were evaluated in five stroke survivors walking with a powered knee exoskeleton using leave-one-subject-out hyperparameter selection and sequential test-then-adapt Stage 2 replay. Relative to the non-adapted baselines, Stage 1+2 reduced the mean participant-wise phase root mean square error by 84.2%, 77.0%, and 60.7%, respectively. The Transformer achieved the lowest final error (2.90 +- 1.13$% of the gait cycle) and heel-strike timing error (23.7 +- 4.5ms). Policy-specific ablations showed that every-cycle updates generally produced the lowest or near-lowest error, whereas conditional updating reduced the update frequency with small accuracy differences. After personalization, alignment produced model-dependent changes in phase error while preserving or improving heel-strike detection and reducing heel-strike timing error for the LSTM and Transformer. Concurrent embedded tests showed that the TCN and Transformer maintained 100-Hz inference during Stage 2 updates without deadline misses, whereas the LSTM missed the 10-ms deadline in 6.6% of inferences. All updates completed within 0.8s. These results support the offline feasibility and embedded computational timing of the proposed framework for exoskeleton-assisted walking.

Abstract: Hip exoskeletons may improve recovery from unexpected gait perturbations, yet personalizing assistance remains difficult because balance is multidimensional and human-in-the-loop experiments are small-sample and noisy. We present a participant-specific composite balance cost that integrates seven biomechanical sub-metrics spanning margin of stability, center-of-mass dynamics, and whole-body angular momentum. The sub-metrics are converted to direction-aligned, dimensionless cost features, and nonnegative fusion weights are learned on the simplex. Coupled with an empirical-Bayes hierarchical model, the learned-composite selector estimates each tested condition's posterior probability of being best, P(best), and a high-probability candidate set with size $K_{0.8}$. The framework was evaluated with three participants walking at 1.1 m/s during unilateral belt-slip perturbations across 46 hip-assistance conditions. In the full-budget analysis (B = 4 repeats per condition), the selector concentrated 80% of the posterior probability within 1 to 5 of 46 conditions, compared with 2 to 12 for equal-weight fusion and 4 to 37 for principal component analysis fusion. This smaller candidate set could shorten personalization experiments and limit participants' exposure to repeated perturbations in future studies. Selected-condition trials showed lower observed composite costs than no-torque trials, with nominal p < 0.05 for P2 and P3. Leave-one-repeat-out refits yielded positive mean held-out rank correlations for all participants and moderate stability of the learned weights and candidate sets. These proof-of-concept results support participant-specific composite balance evaluation for candidate selection in perturbation-based human-in-the-loop experiments.