Papers for
public health analysts
Papers whose findings have a practical use for this group, as judged from the abstract. Open a paper to read what it means in practice.
Geospatial models reveal health insights missing in social risk data
Geospatial Foundation Models Capture Health-Relevant Dimensions of Place Beyond Conventional Social Risk Indices
Abstract: Area-based social risk indices summarize residents' socioeconomic conditions but incompletely capture physical features of place that may affect health. We evaluated whether numerical representations of physical place produced by four geospatial foundation model families from 2022 satellite data explained residual variance in tract-level associations between the Area Deprivation Index, Social Deprivation Index, and Social Vulnerability Index with health outcomes. We used LightGBM to predict variables from the American Community Survey and 40 chronic disease and health-behavior outcomes from CDC PLACES across 82,646 census tracts in the contiguous United States, evaluating performance across 10 held-out states. Among survey variables, models were moderately predictive of some variables including housing type (R-squared up to 0.54) but weak for disability, unemployment, and income disparity. For health outcomes, models explained up to 54% of variance left unexplained by social risk indices, with the largest gains for annual checkups, arthritis, and high blood pressure. Mean total variance explained by geospatial foundation models across the 40 health-related outcomes increased from 0.31 in the smallest tract-size decile to 0.39 in the largest. Geospatial foundation models capture health-relevant features of place not represented by conventional social risk indices and may usefully augment them in epidemiological analyses.
Large language models partially mimic survey responses after health intervention
How Well Do LLMs Simulate Survey Responses Following a Breast Cancer Screening Intervention?
Abstract: Collecting survey data is laborious and limited by privacy constraints. Large language models (LLMs) have shown promise as predictive social simulations. It is unclear whether they can replicate population-level response distributions before and after a healthcare intervention. Using information derived from 4125 women aged 35-59 years, we evaluate whether agents informed solely by pre-intervention profile information can reproduce post-intervention response distributions. Groups of LLM agents (n=50) were created with Gemma 4 E4B and Qwen3.5 9B; conditions ranged from zero-shot prompting to agent profiles enriched with aggregate or individual-level demographic characteristics and pre-intervention questionnaire responses. We compared predicted and observed response distributions with Total Variation Distance (TVD) and Normalized Wasserstein Distance (NWD). Across both LLMs, profile-based agents improved distributional accuracy relative to zero-shot and random baselines. Nevertheless, direct sampling of 50 real participants remained more accurate. Prediction errors were also higher among participants aged 55-59 years and those living in private property. Errors also varied by question theme and LLM model, with the highest errors observed for cancer fatalism and post intervention attitudes toward genetics. Sensitivity analyses showed that performance was influenced by prompt template changes and temperature hyperparameter. Our results show the potential of LLM-based agents to model behavioral responses to interventions in silico. However, profiles containing additional information beyond demographics did not consistently outperform simpler ones. Certain cultural constructs and population groups also remain inadequately represented by the LLM models evaluated. Future work may include building behaviorally grounded and locally validated virtual populations.