Abstract: Post-training quantization reduces the deployment cost of vision-language models (VLMs), but preserving multimodal capabilities at low bit widths remains challenging. Existing methods rely on modality- or token-level gradient statistics, which are susceptible to cross-sample variations in visual-to-textual token ratios and the positions of visual information, limiting statistical stability. Moreover, overly coarse aggregation through absolute values and averaging discards gradient signs and channel-wise differences, limiting the separation of modality-specific sensitivities. In contrast, the channel space provides a shared coordinate system across samples, making it a more natural basis for capturing stable task-sensitive structures. We therefore propose SubRot, a signed gradient subspace calibration method for VLM rotation quantization. Through eigendecomposition of the empirical Fisher matrix of activation gradients, SubRot identifies a sensitive channel subspace with three properties: cross-sample stability, clear sensitivity separation, and consistent signed effects on the autoregressive loss along certain directions. Guided by a local Taylor expansion, SubRot combines signed first-order guidance along sign-stable directions with second-order constraints along the remaining sensitive directions, while retaining MSE for overall reconstruction quality. This objective steers quantization errors toward loss-decreasing directions while controlling their magnitude. Experiments on five VLMs across five benchmarks show consistent average-score improvements over FlatQuant under W4A6 and W4A4, reaching 1.4 percentage points on LLaVA-NeXT-7B. Under W4A4, average accuracy degradation from FP16 remains within 1.4 percentage points across all evaluated models, while LLaVA-v1.5-13B exceeds its FP16 average score by 0.4 percentage points.