Abstract: Modern software development increasingly relies on using multiple programming languages. Some software packages are published to multiple package ecosystems such as NPM for JavaScript and PyPI for Python. Little is known about cross-ecosystem packages, especially regarding how they are structured. In this paper, we conduct a large-scale empirical study of over six million packages across six major ecosystems to understand 1) how prevalent cross-ecosystem packages are among all packages, 2) whether there are distinct source code architectural patterns that cross-ecosystem packages use, and 3) whether there are correlations between architectural patterns and project health metrics from GitHub. Results indicate that cross-ecosystem packages constitute a small but important, growing fraction of packages. We identify five distinct architectural patterns. For example, packages that implement code generation from a shared source file or use language bindings are associated with significantly higher community visibility and development activity. Based on our findings, we provide implications for package adopters, maintainers, and researchers. We envision our taxonomy being used for future investigations into several aspects of software development, such as the trade-offs between focusing on one language and translating to other languages using bindings, templating, and wrappers, versus using native code and native functions to support additional languages.