medical imaging specialists

Abstract: Detector response nonuniformity introduces systematic projection errors and ring artifacts in photon-counting detector computed tomography (PCD-CT). In measured PCD-CT data, residual stripe amplitudes vary slowly with projection angle, which fixed-bias models cannot adequately capture. We propose TRACE, a two-stage unsupervised sinogram decomposition method for estimating and correcting these response-related errors. TRACE represents stripes as a fixed bias plus low-order discrete cosine transform (DCT) components, using a small number of coefficients to describe angular variations at each detector element. A learnable analysis--synthesis architecture represents the ideal projections, while two-stage optimization separates them from fixed and then dynamic stripes. An angular-gradient soft orthogonality constraint suppresses correlated variations within the shared DCT gradient subspace, reducing the leakage of object structures into the artifact estimate. All parameters are optimized directly on the measured sinogram without paired training data. Experiments on measured QRM mouse phantom and porcine trotter data show that TRACE suppresses ring artifacts and improves image uniformity while preserving edge sharpness, soft-tissue texture, and trabecular detail.

Abstract: Hyperspectral images (HSIs) are often degraded by mixed noise, including band-dependent Gaussian perturbations and structured artifacts such as stripes, dead-lines, and impulse noise. Most deep denoisers regress the clean image directly, entangling signal and structured noise. We instead model HSI denoising as $\Y=\A\X+\Snoise+\Nnoise$, where $\A\X$ is a low-rank spectral-subspace (unmixing) reconstruction, $\Snoise$ is structured sparse noise and $\Nnoise$ is residual Gaussian noise. The resulting regularized optimization problem is unrolled into AXS-Net, a $K$-stage alternating proximal-point framework. Each stage combines an analytic spectral-basis gradient step, an SSX-Block proximal operator for abundance coefficients, and an SBlock proximal operator for the structured residual with column-consistent and sparse priors. This optimization correspondence exposes interpretable endmembers, abundance maps, and structured-noise estimates. Across ICVL, CAVE, and Harvard datasets and five noise configurations, the proposed AXS-Net achieves strong in-domain accuracy and competitive zero-shot transfer, with consistent gains across all five noise regimes on ICVL and Harvard. The recovered structured-noise closely follows the synthetic reference, and the recovered spectral basis is smooth and band-ordered rather than an arbitrary set of latent channels.

Abstract: Images are important tools in various sciences. Despite the development of photo-taking tools, creating clear and image without noise remains challenging in practice. In particular, Poisson noise has an effect on medical and astronomical images, and reduces their quality. Additionally, blur is another factor that has an effect on image quality. The problem of image restoration becomes very complicated when we have no information about the Point Spread Function (PSF). These types of problems are known as blind case. However, in some images, such as some astronomical images, the type of PSF can be specified, and these types of problems are known as nonblind problems. Total Variation (TV) is a widely used method for solving such inverse problems, where the selection of the penalty function is the most critical factor that affects the method's performance. In this paper, to improve edge preservation, we employ a reweighted $\ell_1$-regularization of the fractional order derivative. Furthermore, we propose a nonblind and blind image deblurring approach under Poisson noise using the Minimax Concave Penalty (MCP), which is a continuous, sparsity promoting, and nearly unbiased regularizer. This formulation leads to a nonconvex optimization model. To solve the proposed model, we introduce an efficient numerical algorithm based on the Alternating Direction Method of Multipliers (ADMM) and provide an analysis of its convergence. Finally, the effectiveness of the proposed algorithm are demonstrated through extensive experiments on various images.