Abstract: Maritime systems operate in highly dynamic environments where unexpected equipment failures can compromise safety, reliability, and operational efficiency. Recent advances in artificial intelligence (AI), machine learning, digital twins, and predictive maintenance enable proactive failure prediction and prevention. However, ensuring trustworthy and explainable decision-making remains a major challenge in safety-critical maritime applications. This chapter reviews key AI technologies required for explainable failure prediction and prevention in maritime systems and presents a conceptual architecture capable of supporting autonomous or human-in-the-loop corrective actions. This architecture integrates data acquisition, time-series forecasting, anomaly detection, risk assessment, decision-making, and explainable AI into a closed-loop framework. With reference to the architectural components, a review and discussion of relevant maritime studies is performed, outlining their methods, advantages, and limitations. Furthermore, it highlights current challenges, including uncertainty and robustness, model generalization, explainability, limited availability of maritime datasets, and operational deployment, and identifies future research directions toward trustworthy AI-assisted maritime decision-making.