Papers for
hospital it teams
Papers whose findings have a practical use for this group, as judged from the abstract. Open a paper to read what it means in practice.
PathCowork trains AI by watching how pathologists work slides
PathCowork: Learning from real-world pathology practice to build AI copilots
Abstract: Medical AI learns from the answers doctors record, but rarely from how they interpret the evidence to reach them. Here we introduce PathCowork, a framework that turns pathologists' narrated examinations into supervision for visual grounding and procedures that guide diagnostic AI agents. Synchronized gaze, narration and navigation link visual findings to the process of interpreting them. Across 48 sessions from 16 pathologists, the platform captured 1,028 minutes of slide review. Using these data, we trained PathCowork-1T for server deployment and PathCowork-27B for local deployment, with improved visual grounding. Across five organ-specific evaluations, agents combining this grounding with recorded diagnostic procedures achieved primary task scores averaging 17.9 and 24.1 percentage points higher than Claude Code and Codex, respectively, with shorter processing times and lower inference costs. Compared to the state-of-the-art multiple-instance learning AIs, the PathCowork agent-proposed regions achieved higher prostate-grading scores with limited slide labels. PathCowork can also help construct pathology AI benchmarks where questions derived from the recordings identified difficulties in recognizing viewing context and rejecting inapplicable premises. In summary, PathCowork proposes a new paradigm to scale up the data collection and train pathology AI through transparent reasoning from diagnostic sessions, opening a path towards systems that learn directly from routine clinical practice.
Surgical phase recognition improves accuracy and stabilizes workflow predictions
Shifted Window Temporal Transformer for YOLO-Guided Phase Recognition in Laparoscopic Cholecystectomy Surgery
Abstract: Intelligent operating rooms require accurate awareness of surgical workflow for better intra-operative decisions, teamwork, and surgical documentation. Therefore, accurately recognizing surgical phase during surgery is crucial. However, previous artificial intelligence-based methods provide fluctuating predictions for the transitions, restricting their clinical use. To address this challenge, we propose a clinically meaningful framework that integrates a Swin Transformer and Temporal Transformer Encoder (TTE) for effective surgical phase recognition and a parallel YOLOv11s network for real-time surgical instrument localization. To avoid phase flickering and to produce stable workflow predictions, a causal temporal smoothing is applied. The proposed framework is tested on the Cholec80 dataset for the simultaneous recognition of the surgical phases and instruments. The overall phase recognition accuracy of this model was 92%, and the macro average F1-score was 0.86. This performance surpasses CNN based methods such as EndoNet (81.7%) and SV-RCNet (85.3%), as well as temporal convolutional and transformer-based approaches including TeCNO (88.6%), Trans-SVNet (90.9%), and LoViT (91.5%). Besides, the module of instrument detection achieved mAP@0.5 = 0.863. The reliability of the results is confirmed, obtaining a high recognition rate of the workflows, and a high accuracy of the localization of the instruments. The proposed framework can serve as a foundation for intelligent surgical assistance, enriching situation awareness, and potential robotic surgery applications. Code will be made publicly available at: https://github.com/ac005sheekar/LapChol-Surgery-Swin-Cholec80
Large language model platform supports hospital tasks inside secure network
The LLENS Platform for On-Premises Large Language Model Agents in a Japanese University Hospital: Development and Evaluation Study
Abstract: Large language model agents that use tools could take on part of the electronic health record and desk work that occupies physicians' time, but in many hospitals the medical information systems run inside closed networks, so the model and the agent harness must also sit inside. We designed, implemented, and deployed LLENS, a clinical support AI agent platform that runs inside the closed network of Hokkaido University Hospital on one host with 8 NVIDIA H200 GPUs, the open-weight model Kimi K2.6 (~1 trillion parameters), and a web application rebuilt from Open WebUI. The harness has 10 components, including page image reading, full-text attachment input, a path-addressed document tree without a vector index, a network-isolated sandbox, artifact return, self-checking of generated output, subagents, and saved procedures. Kimi K2.6 was chosen from 3 open-weight candidates and scored 480/500 on the 2026 Japanese Medical Licensing Examination; it generated 119 tokens/s for one user and served 16 concurrent requests at 908 tokens/s in total. On 180 questions over hospital documents (3 seeds each), mean accuracy was 10.7% with no documents, 81.3% with fixed retrieval (top 10 chunks of one lexical search), and 97.2% with interactive access, in which the model reads with document tools and the sandbox (15.9 percentage points above fixed retrieval, 95% CI 10.9-21.3); the difference lay in filtering/counting questions (16.7% vs 87.8%). Five scenarios with synthetic data ran on combinations of the components: needlestick injury response, batch adverse event grading, scanned referral letter transcription, falls data aggregation and plotting, and investigation of 3 topics by subagents. The platform has run on the hospital network since September 14, 2026.
Compact chest X-ray model improves disease localization using report hints
APED-CXR: Adaptive Privileged Evidence Distillation for Chest X-Ray Grounding with Image-Only Inference
Abstract: Compact chest X-ray (CXR) models that localize findings suit deployment, but box annotations are limited and report-aware multimodal models are expensive at inference. We introduce APED-CXR, which distills report-informed spatial evidence from a frozen multimodal teacher into a student with 11.1M parameters that predicts diseases and boxes from shared evidence maps and requires the image alone at test time. During training, the teacher uses the radiograph, report, and queried class to evaluate regions proposed from the student's current evidence maps, and its support scores serve as training targets for the student's pooled evidence scores within these regions. Trained on PadChest and evaluated on held-out PadChest-GR, refreshing the student's proposals for teacher evaluation improves box-level localization F1 from 0.302 with fixed warm-up proposals to 0.338 (IoU >= 0.5; gain 0.036, 95% CI [0.022, 0.049]), while maintaining diagnostic AUC. This gain depends on the teacher checking current proposals: with equally many random boxes, a fixed dense box set, teacher-generated boxes, or report rules instead of the teacher, F1 stays near the fixed-proposal level, and proposals two refreshes old recover only part of the gain. On NIH ChestX-ray14, a secondary test set, box recall also rises from 0.423 to 0.447.
Multi-agent system improves drug safety for complex patient care
PRISMATIC : Prescription Risk Inspection System for Multi-Agent Treatment Interaction in Clinical Decision-Making
Abstract: Medical prescribing errors for multimorbid patients, who require complex drug regimens, are a major patient safety concern. These errors often stem from fragmented decision-making across medical specialties, a critical coordination failure that leads to adverse drug events and rehospitalizations. To address this coordination challenge, we introduce PRISMATIC, a multi-agent architecture where specialized agents, each representing a workflow role, collaboratively generate and refine treatment plans. Operating on a blackboard architecture, the system first structures patient information from clinical notes, then iteratively develops safe, rational, and interpretable drug regimens. The agents' collaboration is governed by two novel adaptive coordination mechanisms: (1) Dynamic Self-Updating Weight Adjustment (DSWA), a long-term mechanism that adjusts the influence weights of agents based on historical case outcomes, enabling the system to adapt and trust more reliable specialists over time. (2) Discrepancy Feedback Precise Calibration (DFPC), a short-term mechanism where agents provide iterative feedback to resolve disagreements and eliminate prescription conflicts for the current patient. Experiments on patient records from the MIMIC-IV database show that PRISMATIC significantly reduces drug conflicts, improves prescription coverage, and enhances treatment consistency compared to strong LLM baselines. Our work demonstrates that structuring clinical co-treatment as a multi-agent coordination problem offers a promising path toward safer and more coherent multidisease management.
Healthcare agent evaluation benchmark improves action and workflow quality
MedHarnessBench: A Unified Benchmark for Healthcare Agent Evaluation
Abstract: Healthcare agents must transform longitudinal clinical evidence into reliable actions through heterogeneous tools and stateful workflows, conditions under which model-centric systems may lose context, misuse tools, fail to verify consequential transitions, or cross authorization boundaries. Existing medical-agent benchmarks primarily emphasize terminal task outcomes, making it difficult to determine whether execution failures arise from the agent model, the runtime harness, or their interaction. We present the Medical Harness Protocol, an outcome-preserving framework that independently evaluates seven healthcare-specific process dimensions: Care Action Fulfillment, Clinical Resource Competence, Patient-Evidence Alignment, Clinical Workflow Continuity, Clinical Auditability, Closed-Loop Verification, and Clinical Conduct Boundaries. A normalized intervention trace further tracks whether runtime support is available, activated, delivered, adopted by the agent, and propagated into subsequent behavior. We instantiate the protocol as MedHarnessBench, comprising 342 executable tasks across FHIR/EHR operations, healthcare-administration interfaces, and multimodal clinical tools. Across more than 16,000 controlled task executions, MedHarness yields broad improvements in terminal task success, intermediate subtask completion, and healthcare-specific process quality. We further evaluate MedHarness against multiple general-purpose harnesses and use controlled single-fault perturbations to verify the sensitivity and discrimination of the seven-dimensional evaluation. These results demonstrate that healthcare-specific runtime support can substantially improve both task completion and execution quality, while revealing failures that terminal outcomes alone cannot capture. Code and resources are available at https://github.com/Tomry1114/Awesome-Agent-Harness-for-Healthcare.
BrainAid enables efficient brain tumor detection on low power devices
BrainAid: Efficient Brain Tumor Detection Using Lightweight CNNs and Explainable AI for Resource-Constrained Environments
Abstract: A brain tumor is an unusual growth of cells in the brain that can be cancerous or not, affecting normal brain function and causing serious risk to health. Existing solutions for brain tumor classification, such as expert manual evaluations of magnetic resonance imaging (MRI) scans, are generally inconsistent as different professionals have different criteria and can be resource-intensive, leading to delayed diagnoses. Additionally, while deep learning models have demonstrated potential, they typically require significant computational resources, motivating the need for more efficient and accessible diagnostic tools that can be deployed in real-time healthcare settings. To address these limitations, this study presents BrainAid, which makes efficient use of Convolutional Neural Networks (CNNs) and Vision Transformers (ViTs) for effective classification of four-class classification of glioma, meningioma, pituitary tumor, and no-tumor MRI scans, outperforming all the standard models such as VGG16, Inception-V3, ResNet-50 and so, while integrating Explainable AI (XAI) to improve interpretability. The BrainAid is trained to classify tumors with a high precision of 98%, achieving an F1 score of 98% and an accuracy of 98% using publicly available dataset. The model is deployed on a Raspberry Pi, demonstrating efficiency in low-resource environments. This system shows the feasibility of real-time, edge-based tumor classification, providing quick diagnostic support for medical professionals and enhancing patient care in resource-limited healthcare facilities and underserved areas.
Clinical AI platform matches top scribes in note quality and flexibility
Symphony for Text Generation: Benchmarking Clinical Note Generation
Abstract: Ambient documentation systems are rapidly gaining adoption, yet their impact on clinical note quality remains poorly characterized. We introduce MedConv, a multilingual dataset of 300 clinical encounters in English, Danish, and German, and use it alongside the Ambient Clinical Intelligence benchmark (ACI-BENCH) to compare Corti, a clinical AI platform, with two leading, accessible ambient scribe software applications built on general-purpose AI. We present a controlled clinical evaluation framework that combines entailment metrics with LLM-judged pairwise comparisons across eight dimensions adopted from PDSQI-9. Results show that Corti's API-based text-generation infrastructure is on par with or outperforms leading commercial scribes. We further show that Corti's configurable API provides the flexibility necessary to fine-tune quality dimensions for specific documentation use cases. We present the evaluation methodology and release a dataset to support future reproducible comparison of ambient documentation systems.
Multimodal method improves gastric cancer subtype classification accuracy
Multimodal Knowledge Distillation for Gastric Adenocarcinoma Classification from Whole-Slide Images
Abstract: Gastric adenocarcinoma (GA) is a leading cause of cancer-related mortality worldwide, and accurate histopathological subtype classification from whole-slide images (WSIs) is essential for effective treatment planning. While multimodal approaches that integrate pathology report text with WSIs can improve classification, existing methods often depend on computationally expensive transformer architectures and large language models. We propose a multimodal knowledge distillation (MKD) framework that combines a pretrained WSI image encoder and a clinical text encoder using Low-Rank Multimodal Fusion (LMF) to efficiently model cross-modal interactions during training. Each WSI is represented as a bag of patches paired with a slide-level diagnostic caption. The teacher model learns fused image-text representations for subtype classification, while the student model distills this knowledge to enable accurate image-only inference. We evaluate our method on the PatchGastric benchmark dataset and achieve at least 3.35% higher mean accuracy than state-of-the-art approaches, without relying on transformer-based fusion, multi-task learning, or large language models. The source code is available at https://github.com/helomelo1/MKD-LMF.
Hybrid AI model improves breast cancer detection in African clinics
Hybrid Cross-Modal Attention Network for Early Breast Cancer Detection in Low-Resource Clinical Settings
Abstract: Breast cancer is the leading cause of cancer-related mortality among women in Sub-Saharan Africa, where delayed diagnosis results from limited radiology expertise and fragmented clinical data systems. Although deep learning models have demonstrated strong performance in mammographic analysis, most rely solely on imaging data and are trained on Western populations, limiting their applicability in African healthcare settings. This paper presents a Hybrid Cross-Modal Attention Network (HCMAN) that integrates mammogram images with structured clinical data using transformer-based cross-modal attention mechanisms. The model was developed and validated using a locally collected dataset of 2,560 mammogram images from 1,024 patients across four Ethiopian referral hospitals, with biopsy-confirmed ground truth labels. The proposed framework achieves 97.8% accuracy, 97.2% sensitivity, 98.3% specificity, and an AUC of 0.987, significantly outperforming image-only baselines. The system demonstrates robustness to low-quality images typical of resource-limited settings, with only 3.2% performance degradation compared to 8.7% for image-only models. Cross-modal attention analysis reveals clinically appropriate behavior: higher reliance on clinical features for ambiguous cases such as dense breasts and young patients. The model's lightweight architecture enables deployment on standard hospital workstations (<2 seconds inference on CPU). This work advances sustainable, context-aware AI solutions for equitable breast cancer diagnostics in Africa.
Spatial gating improves accuracy of AI radiology report generation
Diagnosis-Conditioned Spatial Gating and Decoder-Level Supervised Contrastive Learning for Radiology Report Generation
Abstract: Radiology report generation models can produce fluent text while still containing finding-level inaccuracies. Diagnosis-driven methods improve generation by conditioning on predicted findings, but these predictions do not directly modify the visual patch features provided to the decoder, and global gating applies the same modulation across spatial locations. We introduce a Position-Aware Gate (PAG) that uses predicted finding representations to modulate visual patches spatially without region supervision. We also propose a Decoder-level Supervised Contrastive Loss (DSCL) that structures decoder representations using shared positive findings rather than instance identity. On MIMIC-CXR, PAG+DSCL improves clinical efficacy (CE) F1 from 0.484 to 0.502 over a matched global-gate reference, while PAG and DSCL individually reach 0.491 and 0.495. Without additional fine-tuning, the combined model achieves 0.226 CE F1 on IU X-Ray, compared with 0.211 reported by PromptMRG.
Multipath routing boosts patient mobility and energy use in body sensor networks
Mobility Enhancement of Patients Body Monitoring based on WBAN with Multipath Routing
Abstract: One of the promising applications of wireless sensor networks (WSNs) is monitoring of the human body for health concerns. For this purpose, a large number of small sensors are implanted in the human body. These sensors altogether provide a network of wireless sensors (WBANs) and monitor the vital signs and signals of the human body; these sensors will then send this information to the doctor. The most important application of the WBAN is the implementation of the monitoring network for patient safety in the hospital environment. In this case, supporting patients' mobility is one of the basic needs, which has been underestimated in recent studies. The problem that involves providing the required energy for the units used in this type of network is challenging; for this reason, sent/received units with very low power consumption and with a very small radius are used in order to save energy. The resulting small sending range leads to the lack of support for patients' mobility. In this paper, the ad hoc mode is suggested for use to establish a network and a multipath routing algorithm for the purpose of supporting patients' mobility in a hospital setting. The results of the simulation show that, in addition to supporting patients' mobility, the use of the proposed idea instead of previously presented protocols reduces delays in data transmission and energy consumption; it also increases the delivery rate depending on the destination and the lifetime of the network, while increasing routing overhead.
Ethereum voting prototype offers public audit for hospital ethics committees
A Lightweight Ethereum Voting Prototype for Hospital Ethics Committees with Receipt-Based Inclusion Verification
Abstract: This paper presents a Solidity, Hardhat, React, MetaMask, and ethers.js prototype for hospital ethics committee voting. Role controls, case-state checks, duplicate vote controls, and a receipt hash support public audit and transaction inclusion verification. Because vote events expose wallet addresses and vote values, the design provides pseudonymous auditability, not anonymous or secret-ballot voting; the receipt is neither receipt-free nor coercion-resistant. Evaluation reports 22 passing functional tests and local Hardhat gas use, including 284,137 gas per vote. A 12-participant simulation used assumed probabilities and is not human-subject evidence. Residual risks include multiple wallets, administrator or frontend compromise, credential reassignment, front-running, denial of service, and untested adversarial paths. Confidential deployment requires governed enrollment, encrypted ballots, independent audit, adversarial testing, reproducible benchmarks, and a real user study.
Hierarchical method maps lesions and revisits during colonoscopy video analysis
Lesion-centered 3D mapping of colonoscopy procedures: validation of a hierarchical ensemble pipeline on public benchmark videos
Abstract: Background and Objective: Colonoscopy recording practice preserves text reports and still photographs, while the spatial information already present in the recorded video - where the scope traveled, where a lesion was observed, and whether the same lesion was seen again - is discarded when the procedure ends. This study determines whether a lesion-centered spatial record can be assembled and validated without full-colon 3D reconstruction. Methods: A four-layer hierarchical pipeline was assembled - (1) a global topological map, (2) lesion-level spatio-temporal tracks, (3) on-demand local 3D reconstruction, and (4) persistent lesion identity across repeated observations - and ran end to end on four public videos (two C3VDv2 sequences with ground-truth depth and two full REAL-Colon procedures; 40,245 frames). All components are published, individually validated methods; the contribution is their lesion-centered assembly, linking rules, and evaluation. Results: Revisits, impossible under forward-only mapping by construction, were detected by entry-map Bayesian localization: 5,614 and 4,043 revisit events (56 and 68 distinct nodes) in the two full procedures. Lesion-identity merging at the adopted threshold 0.5 maintained ground-truth purity 1.0 while auto-merging 20 of 231 candidate pairs. The endoscopy-specific geometry engine outperformed a general-purpose foundation model on all metrics (overall absolute relative error (AbsRel) 0.2276 vs. 0.3523). Conclusions: The results are partial but establish a concrete near-term path: revisit detection, lesion identity, and local 3D each returned quantitative, reproducible output without waiting for complete geometric reconstruction; validating the record on clinical data is the next step.
LightMedSeg achieves stroke lesion segmentation with far fewer parameters
LightMedSeg-ISLES: Stroke Lesion Segmentation with 81x Fewer Parameters than nnU-Net
Abstract: Large networks and ensembles often lead medical image segmentation challenges, but their storage and inference demands complicate deployment. We present LightMedSeg-ISLES, a 1.26-million-parameter pipeline for T1-weighted stroke lesion segmentation in ISLES'26. On a 146-case held-out cohort, flip test-time augmentation produces 0.618 mean Dice and 0.599 lesion-wise F1. A 102.35-million-parameter nnU-Net ResEnc-L produces 0.634 Dice and 0.544 lesion-wise F1 after size filtering. LightMedSeg therefore retains 97.5\% of nnU-Net's Dice with 81.4$\times$ fewer parameters while improving lesion-wise F1 by 0.055. Its four-pass TTA operating point requires 4.7$\times$ fewer FLOPs per standardized patch than nnU-Net. It also slightly exceeds filtered UNETR++ and nnFormer. Longer training and stronger augmentation add 0.0358 Dice without increasing capacity, establishing a strong single-checkpoint alternative to much larger models.
Data driven framework ranks hospital processes for automation investment
A Data-Driven Framework for Identifying and Prioritizing RPA Opportunities in Healthcare Processes
Abstract: Robotic Process Automation (RPA) is widely used to reduce administrative burden in United States hospitals, yet an estimated 30-50% of RPA initiatives underperform because processes are selected informally, without a repeatable method to catalogue candidates, prioritize them, match each to an automation tier -- a Python bot, an open-source orchestrator such as n8n, or an enterprise platform such as UiPath -- and forecast financial return before committing resources. We propose a four-module, data-driven framework unifying these decisions: a Process Taxonomy of twenty recurring hospital processes across five value streams; a Prioritization module deriving an Automation Suitability Index from an Analytic Hierarchy Process matrix with an explicit consistency check; a Tool-Tier Selection module recommending the least-cost technology sufficient for a process complexity, integration, and compliance profile; and a Return-on-Investment module quantifying labor savings, error-cost avoidance, payback, and net present value. Applied to a synthetic portfolio spanning all twenty processes, plus a reference data-flow architecture linking it to hospital EHR/payer/ERP systems: 12 of 20 clear the prioritization threshold; the ranking is robust to +/-20% weight perturbation (Spearman correlation 0.83, top-5 set preserved 97.7%, 2,000 Monte Carlo trials); an Automation Risk Index flags four qualifying processes as Critical risk; a budget-constrained portfolio optimization shows diminishing marginal NPV as spend scales from $400K to $1.03M; and a second Monte Carlo analysis shows portfolio NPV stays positive at its 5th percentile. The framework is a conceptual synthesis of the literature rather than an instrument calibrated on primary hospital data; we discuss HIPAA governance and a research agenda for empirical validation. A supplementary Python implementation accompanies the paper.