Papers for
electronic health record developers
Papers whose findings have a practical use for this group, as judged from the abstract. Open a paper to read what it means in practice.
Beacon-SP uses graph and ontology to improve suicide risk assessment
BEACON-SP: Ontology-Grounded GraphRAG Framework for Clinical Suicide Risk Assessment
Abstract: We present BEACON-SP, an ontology-grounded Graph Retrieval-Augmented Generation (GraphRAG) framework for clinician-facing decision support in behavioral health settings such as suicide prevention, where effective assessment requires integrating heterogeneous clinical, behavioral, social, and temporal evidence. BEACON-SP combines patient knowledge graphs with ontology-guided retrieval to support multi-hop reasoning across diagnoses, medications, risk and protective factors, life events, and temporal relationships. The framework is enabled by a comprehensive suicide prevention ontology that integrates the Three-Step Theory, the Integrated Motivational-Volitional Model, and the Suicide Social Determinants of Health Ontology into a unified representation of patient risk factors. We construct ontology-grounded patient knowledge graphs and evaluate BEACON-SP for clinician-facing question answering. Compared with a vector-based retrieval-augmented generation (RAG) baseline on a 1,500-query benchmark spanning 15 clinical categories and 100 patients, BEACON-SP improves completeness, clinical relevance, and evidence grounding under a corrected comparative evaluation protocol, with a small gain on factual accuracy. In paired criterion-level comparisons, GraphRAG is preferred in 76.4% of cases. These results demonstrate the potential of ontology-guided GraphRAG to provide structured, contextualized patient evidence for clinical decision support.
Large language model automates clinical note clarifications with mixed success
Closing Ambient Clinical Documentation Gaps with Automated Provider Queries
Abstract: Provider queries are clarifying requests sent by clinical documentation specialists to physicians to close gaps in the clinical note and ensure accurate billing. Prior work automates note drafting, ICD-10 coding, and order extraction assuming a complete transcript, leaving these gaps unaddressed. We study whether an LLM can automate the query loop, termed DAU (Draft, Ask, Update), across those three tasks. An audit of 3,000 real visits identifies the sources of missing documentation, from which we build five transcript-degradation benchmarks on public data. Analyzing 21k clarification turns on real conversations, we find useful-question predictors are task-specific: oracle confidence dominates, but note completeness needs only simple recall questions while ICD-10 coding needs harder, multi-option ones. About 9% of turns hurt performance, driven by redundant questions and non-answers that still trigger a rewrite. Deployment depends on learning "when not" as much as "what to" ask.
Dual-agent system improves analysis of clinical data with sql checks
Large Language Models for Structured Clinical Data Analysis: Dual-Agent Grounding and Validation
Abstract: Objective: To develop and characterize CLEAR-Med, a dual-agent framework for natural-language analysis of structured clinical data that separates SQL-based invocation from independent validation. Methods: CLEAR-Med uses one agent to translate a question into executable Structured Query Language (SQL), retain the executed query and database result, and produce a draft. Deterministic checks and a separately invoked cross-provider Validation Agent then accept the draft, request one bounded repair, or abstain. We formalized the system as a bounded selective pipeline and evaluated CLEAR-Med's configuration and scalability, and the Invocation Agent's accuracy and consistency on a 25-query development benchmark, using a harmonized 21-site neonatal hypoxic-ischemic encephalopathy table containing 532 de-identified infant records and approximately 1,300 variables. Results: CLEAR-Med completed all six nominal scalability configurations, including 500x1300. Across 25 development-benchmark queries repeated five times, the Invocation Agent answered 83 of 125 responses correctly (66.4%; query-cluster bootstrap 95% CI, 48.0-83.2%), compared with 15 of 125 (12.0%; 95% CI, 3.2-22.4%) for the ungrounded ChatGPT baseline, a paired improvement of 54.4 percentage points (95% CI, 36.8-72.0%). Conclusion: CLEAR-Med provides a general architecture for traceable analysis of structured clinical data: numerical claims remain linked to executed SQL, and unresolved cases can fail closed. The reported experiments characterize CLEAR-Med's configuration and scalability and the Invocation Agent's accuracy, while the formal analysis establishes the encoded-property guarantee of the complete control flow; a prospective full-pipeline evaluation of the validation and abstention stages is the next stage of this work.