Abstract: Extreme compression techniques, including vector quantization (VQ) and input-dependent sparsity, can significantly reduce the memory footprint of large language models (LLMs). However, a key challenge remains in translating such compression into practical efficiency. On conventional systolic-array-based accelerators, VQ incurs high dequantization overhead, while the irregular patterns of input-dependent sparsity are difficult to exploit. In this study, we address these challenges with Vortex, an architecture compatible with systolic-array-based accelerators with minimal hardware overhead, bridging the gap between extreme compression and efficient inference. Vortex adopts a bi-flow execution strategy that efficiently supports vector-quantized models across both prefill and decoding workloads, and we further optimize it through systematic design space exploration. On the algorithm side, we propose codebook-wise contextual sparsity to align with VQ execution. Across end-to-end workloads, Vortex achieves $8.03\times$--$23.7\times$ speedup and $5.68\times$--$12.5\times$ energy reduction over state-of-the-art accelerators.