biomedical engineers

Abstract: sEMG is vulnerable to various contaminants that distort signal morphology and spectral content. Accurate signal quality assessment (SQA) is essential for identifying such degradation and ensuring reliable clinical analyses and decisions. Recent neural network-based SQA methods achieve accurate quality estimation by learning complex contamination patterns, yet their black-box nature prevents clinicians from understanding or validating the reported scores and limits adaptability to application-specific quality definitions without retraining. To address these limitations, we propose Prism-SQA, an interpretable and adaptable neural framework that reformulates SQA as a physiology-aware source-separation and verification process. Prism-SQA decomposes each input signal into a clean sEMG component and five contaminant-specific components using a U-Net with bidirectional long short-term memory. Each separated contaminant component is examined by a Contaminant Fingerprint Verifier, which enforces physiological plausibility by comparing its temporal and spectral structure with canonical contaminant signatures. This design allows clinicians to inspect how each contaminant affects signal quality, grounding the assessment in transparent, signal-level evidence rather than opaque latent representations. Quality indices computed from the verified components further enable customization of quality criteria across clinical contexts without retraining. We evaluate Prism-SQA on continuous quality-score estimation using synthesized noisy sEMG from public Ninapro datasets and on binary quality classification using a clinical dysphagia dataset. Results show that Prism-SQA achieves competitive or better performance than contemporary black-box neural methods while providing explicit interpretability and adaptability, advancing toward practical and clinically aligned sEMG SQA.