InquiTree: Evaluating AI Agents in the Scientific Inquiry Loop with Paper-Derived Research Trees

2026-06-08Databases

Databases
AI summary

The authors created InquiTree, a new testing method that treats scientific discovery like a logical tree of steps, to better judge how well AI agents handle research tasks. They tested AI models on real scientific papers and found two main problems: the models tend to lose critical thinking over longer tasks and struggle to handle newer papers published after their training data. This suggests current AI models partly rely on memorizing past info and may need better designs or human help to truly do scientific work reliably. The authors highlight that just making AI handle bigger contexts isn't enough for dependable scientific reasoning.

LLM-based agentsScientific inquiryResearch TreesHypothesis formulationCognitive tunnelingAnomaly detectionParametric memoryInterpolation vs extrapolationAI evaluationLong-horizon interactions
Authors
Shaoyang Cui
Abstract
While LLM-based agents are increasingly used in scientific workflows, it remains unclear whether they are truly qualified for the dynamic and uncertain process of discovery. Existing static evaluations often conflate genuine reasoning with rote memorization. We introduce InquiTree, a diagnostic environment that formalizes scientific inquiry as interactive Research Trees: directed acyclic graphs capturing the logical dependencies among hypothesis formulation, study design, result interpretation, and belief updating. Evaluating agents on a 30-paper test pool and releasing the open-access InquidTree-18(IT-18) subset, we identify two key limitations. First, agents exhibit an "Erosion of Marginal Capabilities": during long-horizon interactions, they develop "cognitive tunneling," where critical judgment and anomaly detection degrade relative to their intrinsic baselines. Second, performance drops on papers published after model training cutoffs, revealing a boundary between interpolation and extrapolation and suggesting that apparent competence is partly driven by parametric memory. These findings indicate that scaling context alone is insufficient for reliable AI scientists; stronger architectures or human oversight may be required to preserve critical evaluation and generalization.